District Mianwali is bounded by district Attock on North-East, Chakwal and Khushab districts on East and Bhakkar on South and NWFP on its West and North-West. River Indus flows across the district from North to South. Three branches of the Thal Canal emerging form Jinnah Barrage on river Indus near Kala Bagh irrigate the vast areas. Another canal called Chashma Link Canal connects river Indus with river Jhelum through Chashma Barrage. District Mianwali is spread over an area of 5,840 square kilometres comprising of following three tehsils Mianwali, Isakhel and Piplan.

The district has extreme hot and cold climate. The maximum temperature during the summer shoots up to 51ºC while the minimum temperature recorded in winter is as low as 2ºC. The average rainfall in the district is about 250 mm.

The district was taken over by PRSP on 25th of Jan, 2005. There are 40 Basic Health Units, 19 ZCDs / GRDs, 2 Unani / Tibbi Disp. and 6 MCHCs